Nitrocellulose Membranes

Achieve high sensitivity, low background, and superior stripping durability for reliable and cost-effective protein analysis across chemiluminescent and fluorescent applications. Read more

Cat.No.

Specification

Price

NCMR022

1 Roll, 0.22µm
30 cm x 3.0 m

$268.00

MINIBN022

Precut, 0.22 µm
7 x 8.5 cm, 10P

$58.00

MIDIBN022

Precut, 0.22 µm
8.5 x 13.5 cm, 10P

$88.00

NCMR045

1 Roll, 0.45µm
30 cm x 3.0 m

$268.00

MINIBN045

Precut, 0.45 µm
7 x 8.5 cm, 10P

$58.00

MIDIBN045

Precut, 0.45 µm
8.5 x 13.5 cm, 10P

$88.00

Consumables compatible with Bio-Rad Mini System.

YamayBio PVDF and Nitrocellulose Western Blotting Membranes: reliable solutions for every application. Both deliver low background for clear, consistent results.
Nitrocellulose provides high protein affinity, good sensitivity, and resolution for routine protein analysis.

KEY FEATURES

Unmatched Sensitivity for Rare Targets

Unmatched Sensitivity for Rare Targets

Built to Withstand Repeated Stripping

Built to Withstand Repeated Stripping

High-Resolution, Ultra-Low Autofluorescence Background

High-Resolution, Ultra-Low Autofluorescence Background

Mouse muscle lysate was separated on a precast gel (AN9325) and transferred using Ice-free Bath Rapid Transfer Buffer (MS8135) at 400 mA for 45 min. Membranes were blocked with Protein-free Blocking Buffer (BM3152) for 15 min, probed with HRP-conjugated antibody (1:25,000, 1 h, RT), and detected by chemiluminescence. Reliable detection down to 0.039 µg protein loading.

High sensitivity detection across protein loading range

Mouse muscle lysate was separated on a precast gel (AN9325) and transferred using Ice-free Bath Rapid Transfer Buffer (MS8135) at 400 mA for 45 min. Membranes were blocked with Protein-free Blocking Buffer (BM3152) for 15 min, probed with HRP-conjugated antibody (1:25,000, 1 h, RT), and detected by chemiluminescence. Reliable detection down to 0.039 µg protein loading.

Mouse muscle lysate, precast gel (AN9325), transferred with Ice-free Bath Rapid Transfer Buffer (MS8135) at 400 mA for 45 min. Blocked with Protein-free Blocking Buffer (BM3152) for 15 min. Probed with GAPDH-HRP (1:25,000, 1 h, RT). Chemiluminescent detection. After initial imaging, membranes were stripped with PS107 buffer and re-probed for four cycles (stripping times: 10, 20, 30, 60 min; total 2 h). Signal integrity maintained through all cycles.

Excellent membrane re-probing performance

Mouse muscle lysate, precast gel (AN9325), transferred with Ice-free Bath Rapid Transfer Buffer (MS8135) at 400 mA for 45 min. Blocked with Protein-free Blocking Buffer (BM3152) for 15 min. Probed with GAPDH-HRP (1:25,000, 1 h, RT). Chemiluminescent detection. After initial imaging, membranes were stripped with PS107 buffer and re-probed for four cycles (stripping times: 10, 20, 30, 60 min; total 2 h). Signal integrity maintained through all cycles.

HeLa cell lysates were separated on a Bis-Tris 4–20% precast gel and transferred using ice-free transfer buffer. Membranes tested included YamayBio PVDF membrane (0.45 µm) and two MilliporeSigma low-fluorescence PVDF membranes (0.45 µm). After blocking for 15 min, membranes were incubated with primary antibodies against HSP60 or GAPDH, followed by incubation with DyLight 550–labeled secondary antibody or DyLight 488–labeled secondary antibody, respectively.

Significantly lower autofluorescence background

HeLa cell lysates were separated on a Bis-Tris 4–20% precast gel and transferred using ice-free transfer buffer. Membranes tested included YamayBio PVDF membrane (0.45 µm) and two MilliporeSigma low-fluorescence PVDF membranes (0.45 µm). After blocking for 15 min, membranes were incubated with primary antibodies against HSP60 or GAPDH, followed by incubation with DyLight 550–labeled secondary antibody or DyLight 488–labeled secondary antibody, respectively.

Specifications

Material type Nitrocellulose
Pore size 0.22 µm / 0.45 µm
Dimensions 30 cm x 3.0 m / 7 x 8.5 cm / 8.5 x 13.5 cm
Format Roll / Sheet

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